A Mutation in the sap Operon Attenuates Survival of Nontypeable Haemophilus influenzae in a Chinchilla Model of Otitis Media

Bacteria have evolved strategies to resist killing by antimicrobial peptides (APs), important effectors of innate immunity. The sap (sensitivity to antimicrobial peptides) operon confers resistance to AP-mediated killing of Salmonella. We have recently shown that sapA gene expression is upregulated...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Mason, Kevin M., Munson, Robert S., Bakaletz, Lauren O.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2005
Sujets:
Molecular Pathogenesis
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538956/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15618200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.73.1.599-608.2005
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