A Mutation in the sap Operon Attenuates Survival of Nontypeable Haemophilus influenzae in a Chinchilla Model of Otitis Media

Bacteria have evolved strategies to resist killing by antimicrobial peptides (APs), important effectors of innate immunity. The sap (sensitivity to antimicrobial peptides) operon confers resistance to AP-mediated killing of Salmonella. We have recently shown that sapA gene expression is upregulated...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Mason, Kevin M., Munson, Robert S., Bakaletz, Lauren O.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2005
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538956/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15618200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.73.1.599-608.2005
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