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Phosphorylcholine Decreases Early Inflammation and Promotes the Establishment of Stable Biofilm Communities of Nontypeable Haemophilus influenzae Strain 86-028NP in a Chinchilla Model of Otitis Media

Nontypeable Haemophilus influenzae (NTHi) is a leading causative agent of otitis media. Much of the inflammation occurring during NTHi disease is initiated by lipooligosaccharides (LOS) on the bacterial surface. Phosphorylcholine (PCho) is added to some LOS forms in a phase-variable manner, and thes...

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Detalhes bibliográficos
Main Authors: Hong, Wenzhou, Mason, Kevin, Jurcisek, Joseph, Novotny, Laura, Bakaletz, Lauren O., Swords, W. Edward
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828519/
https://ncbi.nlm.nih.gov/pubmed/17130253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01691-06
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