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Phosphorylcholine Decreases Early Inflammation and Promotes the Establishment of Stable Biofilm Communities of Nontypeable Haemophilus influenzae Strain 86-028NP in a Chinchilla Model of Otitis Media

Nontypeable Haemophilus influenzae (NTHi) is a leading causative agent of otitis media. Much of the inflammation occurring during NTHi disease is initiated by lipooligosaccharides (LOS) on the bacterial surface. Phosphorylcholine (PCho) is added to some LOS forms in a phase-variable manner, and thes...

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Détails bibliographiques
Auteurs principaux: Hong, Wenzhou, Mason, Kevin, Jurcisek, Joseph, Novotny, Laura, Bakaletz, Lauren O., Swords, W. Edward
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828519/
https://ncbi.nlm.nih.gov/pubmed/17130253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01691-06
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