Development of a Chinchilla Model To Allow Direct, Continuous, Biophotonic Imaging of Bioluminescent Nontypeable Haemophilus influenzae during Experimental Otitis Media

We transformed a nontypeable Haemophilus influenzae clinical isolate with a plasmid containing the luxCDABE operon driven by the H. influenzae outer membrane protein P2 promoter. Herein, we demonstrate the ability to detect bioluminescence and to monitor infection within the nasopharynges, eustachia...

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Bibliographische Detailangaben
Hauptverfasser: Novotny, Laura A., Mason, Kevin M., Bakaletz, Lauren O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Bacterial Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538955/
https://ncbi.nlm.nih.gov/pubmed/15618201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.609-611.2005
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