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BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon

The ability of lysosomes to move within the cytoplasm is important for many cellular functions. This ability is particularly critical in neurons, which comprise vast, highly differentiated domains such as the axon and dendrites. The mechanisms that control lysosome movement in these domains, however...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Farías, Ginny G., Guardia, Carlos M., De Pace, Raffaella, Britt, Dylan J., Bonifacino, Juan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389300/
https://ncbi.nlm.nih.gov/pubmed/28320970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616363114
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