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BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon

The ability of lysosomes to move within the cytoplasm is important for many cellular functions. This ability is particularly critical in neurons, which comprise vast, highly differentiated domains such as the axon and dendrites. The mechanisms that control lysosome movement in these domains, however...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Farías, Ginny G., Guardia, Carlos M., De Pace, Raffaella, Britt, Dylan J., Bonifacino, Juan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389300/
https://ncbi.nlm.nih.gov/pubmed/28320970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616363114
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