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BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon

The ability of lysosomes to move within the cytoplasm is important for many cellular functions. This ability is particularly critical in neurons, which comprise vast, highly differentiated domains such as the axon and dendrites. The mechanisms that control lysosome movement in these domains, however...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Farías, Ginny G., Guardia, Carlos M., De Pace, Raffaella, Britt, Dylan J., Bonifacino, Juan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389300/
https://ncbi.nlm.nih.gov/pubmed/28320970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616363114
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