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BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes Along Different Microtubule Tracks

The multiple functions of lysosomes are critically dependent on their ability to undergo bidirectional movement along microtubules between the center and the periphery of the cell. Centrifugal and centripetal movement of lysosomes is mediated by kinesin and dynein motors, respectively. We recently d...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Guardia, Carlos M., Farías, Ginny G., Jia, Rui, Pu, Jing, Bonifacino, Juan S.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136296/
https://ncbi.nlm.nih.gov/pubmed/27851960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.062
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