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Intramolecular strain coordinates kinesin stepping behavior along microtubules

Kinesin advances 8 nm along a microtubule per ATP hydrolyzed, but the mechanism responsible for coordinating the enzymatic cycles of kinesin’s two identical motor domains remains unresolved. Here, we have tested whether such coordination is mediated by intramolecular tension generated by the “neck l...

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Bibliografski detalji
Glavni autori: Yildiz, Ahmet, Tomishige, Michio, Gennerich, Arne, Vale, Ronald D.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613771/
https://ncbi.nlm.nih.gov/pubmed/18805095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.07.018
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