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Intramolecular strain coordinates kinesin stepping behavior along microtubules
Kinesin advances 8 nm along a microtubule per ATP hydrolyzed, but the mechanism responsible for coordinating the enzymatic cycles of kinesin’s two identical motor domains remains unresolved. Here, we have tested whether such coordination is mediated by intramolecular tension generated by the “neck l...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613771/ https://ncbi.nlm.nih.gov/pubmed/18805095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.07.018 |
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