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Rab5 and its effector FHF contribute to neuronal polarity through dynein-dependent retrieval of somatodendritic proteins from the axon

An open question in cell biology is how the general intracellular transport machinery is adapted to perform specialized functions in polarized cells such as neurons. Here we illustrate this adaptation by elucidating a role for the ubiquitous small GTPase Ras-related protein in brain 5 (Rab5) in neur...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Guo, Xiaoli, Farías, Ginny G., Mattera, Rafael, Bonifacino, Juan S.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018783/
https://ncbi.nlm.nih.gov/pubmed/27559088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601844113
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