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Binding Site of the Bridged Macrolides in the Escherichia coli Ribosome
Ketolides represent the latest group of macrolide antibiotics. Tight binding of ketolides to the ribosome appears to correlate with the presence of an extended alkyl-aryl side chain. Recently developed 6,11-bridged bicyclic ketolides extend the spectrum of platforms used to generate new potent macro...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC538896/ https://ncbi.nlm.nih.gov/pubmed/15616307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.281-288.2005 |
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