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Binding Site of the Bridged Macrolides in the Escherichia coli Ribosome

Ketolides represent the latest group of macrolide antibiotics. Tight binding of ketolides to the ribosome appears to correlate with the presence of an extended alkyl-aryl side chain. Recently developed 6,11-bridged bicyclic ketolides extend the spectrum of platforms used to generate new potent macro...

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Bibliografische gegevens
Hoofdauteurs: Xiong, Liqun, Korkhin, Yakov, Mankin, Alexander S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538896/
https://ncbi.nlm.nih.gov/pubmed/15616307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.281-288.2005
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