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Mitochondrial Ribosome as the Target for the Macrolide Antibiotic Clarithromycin in the Helminth Echinococcus multilocularis

The mitochondrial rRNA of the tapeworm species Echinococcus multilocularis carries an adenine at sequence position 2058 (numbering according to that for Escherichia coli) of the large-subunit rRNA (lsrRNA), while the nucleus-encoded rRNA, as determined in this study, is characterized by 2058G. This...

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Main Authors: Mathis, Alexander, Wild, Peter, Boettger, Erik C., Kapel, Christian M. O., Deplazes, Peter
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196245/
https://ncbi.nlm.nih.gov/pubmed/16048933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3251-3255.2005
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