Mitochondrial Ribosome as the Target for the Macrolide Antibiotic Clarithromycin in the Helminth Echinococcus multilocularis

The mitochondrial rRNA of the tapeworm species Echinococcus multilocularis carries an adenine at sequence position 2058 (numbering according to that for Escherichia coli) of the large-subunit rRNA (lsrRNA), while the nucleus-encoded rRNA, as determined in this study, is characterized by 2058G. This...

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Hlavní autoři: Mathis, Alexander, Wild, Peter, Boettger, Erik C., Kapel, Christian M. O., Deplazes, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
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Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196245/
https://ncbi.nlm.nih.gov/pubmed/16048933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3251-3255.2005
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