Binding Site of Macrolide Antibiotics on the Ribosome: New Resistance Mutation Identifies a Specific Interaction of Ketolides with rRNA

Macrolides represent a clinically important class of antibiotics that block protein synthesis by interacting with the large ribosomal subunit. The macrolide binding site is composed primarily of rRNA. However, the mode of interaction of macrolides with rRNA and the exact location of the drug binding...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Garza-Ramos, Georgina, Xiong, Liqun, Zhong, Ping, Mankin, Alexander
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2001
Gaiak:
Genetics and Molecular Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC95531/
https://ncbi.nlm.nih.gov/pubmed/11698379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.23.6898-6907.2001
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