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Pharmacodynamic Evaluation of Extending the Administration Time of Meropenem using a Monte Carlo Simulation

A Monte Carlo simulation demonstrated that 1 g of meropenem (MEM) every 8 h (q8h) (3-h infusion) has a higher target attainment rate against Pseudomonas aeruginosa than either 500 mg of MEM q8h (3-h infusion) or 0.5 g of imipenem-cilastatin (I-C) q6h (1-h infusion). For other pathogens, 500 mg of ME...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Lomaestro, Ben M., Drusano, G. L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538854/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616337/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.461-463.2005
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