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Pharmacodynamic Evaluation of Extending the Administration Time of Meropenem using a Monte Carlo Simulation
A Monte Carlo simulation demonstrated that 1 g of meropenem (MEM) every 8 h (q8h) (3-h infusion) has a higher target attainment rate against Pseudomonas aeruginosa than either 500 mg of MEM q8h (3-h infusion) or 0.5 g of imipenem-cilastatin (I-C) q6h (1-h infusion). For other pathogens, 500 mg of ME...
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| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.461-463.2005 |
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