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Proteasome-Mediated Degradation of Cotranslationally Damaged Proteins Involves Translation Elongation Factor 1A
Rad23 and Rpn10 play synergistic roles in the recognition of ubiquitinated proteins by the proteasome, and loss of both proteins causes growth and proteolytic defects. However, the physiological targets of Rad23 and Rpn10 have not been well defined. We report that rad23Δ rpn10Δ is unable to grow in...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538794/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15601860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.1.403-413.2005 |
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