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Proteasome-Mediated Degradation of Cotranslationally Damaged Proteins Involves Translation Elongation Factor 1A

Rad23 and Rpn10 play synergistic roles in the recognition of ubiquitinated proteins by the proteasome, and loss of both proteins causes growth and proteolytic defects. However, the physiological targets of Rad23 and Rpn10 have not been well defined. We report that rad23Δ rpn10Δ is unable to grow in...

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Bibliografski detalji
Glavni autori: Chuang, Show-Mei, Chen, Li, Lambertson, David, Anand, Monika, Kinzy, Terri Goss, Madura, Kiran
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC538794/
https://ncbi.nlm.nih.gov/pubmed/15601860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.403-413.2005
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