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Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions

Short Tandem Repeats (STRs) are frequent entities in many transcripts, however, in some cases, pathological events occur when a critical repeat length is reached. This phenomenon is observed in various neurological disorders, such as myotonic dystrophy type 1 (DM1), fragile X-associated tremor/ataxi...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Principais autores: Ciesiolka, Adam, Jazurek, Magdalena, Drazkowska, Karolina, Krzyzosiak, Wlodzimierz J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387085/
https://ncbi.nlm.nih.gov/pubmed/28442996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00097
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