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Inverted Terminal Repeat Sequences Are Important for Intermolecular Recombination and Circularization of Adeno-Associated Virus Genomes

The relatively small package capacity (less than 5 kb) of adeno-associated virus (AAV) vectors has been effectively doubled with the development of dual-vector heterodimerization approaches. However, the efficiency of such dual-vector systems is limited not only by the extent to which intermolecular...

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Hlavní autoři: Yan, Ziying, Zak, Roman, Zhang, Yulong, Engelhardt, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC538689/
https://ncbi.nlm.nih.gov/pubmed/15596830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.364-379.2005
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