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Smad7 knockdown activates protein kinase RNA-associated eIF2α pathway leading to colon cancer cell death
Upregulation of Smad7, an inhibitor of transforming growth factor-β1 (TGF-β1), occurs in sporadic colorectal cancer (CRC) and knockdown of Smad7 inhibits CRC cell growth, a phenomenon that associates with decreased expression of cell division cycle 25 homolog A and arrest of cells in the S phase of...
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| I publikationen: | Cell Death Dis |
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| Huvudupphovsmän: | , , , , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5386514/ https://ncbi.nlm.nih.gov/pubmed/28300830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.103 |
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