The Crebbp acetyltransferase is a haploinsufficient tumor suppressor in B cell lymphoma

Inactivating mutations of the CREBBP acetyltransferase are highly frequent in diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL), the two most common germinal-center (GC) derived cancers. However, the role of CREBBP inactivation in lymphomagenesis remains unclear. Here we show that C...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Zhang, Jiyuan, Vlasevska, Sofija, Wells, Victoria A., Nataraj, Sarah, Holmes, Antony B., Duval, Romain, Meyer, Stefanie N., Mo, Tongwei, Basso, Katia, Brindle, Paul K., Hussein, Shafinaz, Dalla-Favera, Riccardo, Pasqualucci, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386396/
https://ncbi.nlm.nih.gov/pubmed/28069569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-1417
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