Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma

Inactivating mutations of the CREBBP and EP300 acetyltransferases are among the most common genetic alterations in diffuse large B cell lymphoma (DLBCL) and follicular lymphoma (FL). Here, we examined the relationship between these two enzymes in germinal center (GC) B cells, the normal counterpart...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunity
Egile Nagusiak: Meyer, Stefanie N., Scuoppo, Claudio, Vlasevska, Sofija, Bal, Elodie, Holmes, Antony B., Holloman, Mara, Garcia-Ibanez, Laura, Nataraj, Sarah, Duval, Romain, Vantrimpont, Thomas, Basso, Katia, Brooks, Nigel, Dalla-Favera, Riccardo, Pasqualucci, Laura
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362711/
https://ncbi.nlm.nih.gov/pubmed/31519498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.08.006
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak