Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress

Histological inspection of visually normal tissue adjacent to neoplastic lesions often reveals multiple foci of cellular abnormalities. This suggests the presence of a regional carcinogenic signal that spreads oncogenic transformation and field cancerization. We observed an abundance of mutagenic re...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Chan, Jeremy Soon Kiat, Tan, Ming Jie, Sng, Ming Keat, Teo, Ziqiang, Phua, Terri, Choo, Chee Chong, LI, Liang, Zhu, Pengcheng, Tan, Nguan Soon
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386391/
https://ncbi.nlm.nih.gov/pubmed/28102840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.492
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