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Angiopoietin-like 4 induces a β-catenin-mediated upregulation of ID3 in fibroblasts to reduce scar collagen expression

In adult skin wounds, collagen expression rapidly re-establishes the skin barrier, although the resultant scar is aesthetically and functionally inferior to unwounded tissue. Although TGFβ signaling and fibroblasts are known to be responsible for scar-associated collagen production, there are curren...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Teo, Ziqiang, Chan, Jeremy Soon Kiat, Chong, Han Chung, Sng, Ming Keat, Choo, Chee Chong, Phua, Glendon Zhi Ming, Teo, Daniel Jin Rong, Zhu, Pengcheng, Choong, Cleo, Wong, Marcus Thien Chong, Tan, Nguan Soon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524754/
https://ncbi.nlm.nih.gov/pubmed/28740178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05869-x
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