Chromatin Dynamics Regulate Mesenchymal Stem Cell Lineage Specification and Differentiation to Osteogenesis

Multipotent mesenchymal stromal cells (MSCs) are critical for regeneration of multiple tissues. Epigenetic mechanisms are fundamental regulators of lineage specification and cell fate, and as such, we addressed the question of which epigenetic modifications characterize the transition of nascent MSC...

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Publicat a:Biochim Biophys Acta
Autors principals: Wu, Hai, Gordon, Jonathan A.R., Whitfield, Troy W., Tai, Phillip W.L., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385709/
https://ncbi.nlm.nih.gov/pubmed/28077316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2017.01.003
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