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AMPHIPHILIC COPOLYMERS REDUCE AGGREGATION OF UNFOLDED LYSOZYME MORE EFFECTIVELY THAN POLYETHYLENE GLYCOL

Certain amphiphilic block copolymers are known to prevent aggregation of unfolded proteins. To better understand the mechanism of this effect, the optical properties of heat-denatured and dithiothreitol (DTT) reduced lysozyme were evaluated with respect to controls using UV-Vis spectroscopy, transmi...

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Bibliographic Details
Published in:Phys Biol
Main Authors: Chin, Jaemin, Mustafi, Devkumar, Poellmann, Michael J., Lee, Raphael C.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385145/
https://ncbi.nlm.nih.gov/pubmed/28061483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/aa5788
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