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AMPHIPHILIC COPOLYMERS REDUCE AGGREGATION OF UNFOLDED LYSOZYME MORE EFFECTIVELY THAN POLYETHYLENE GLYCOL

Certain amphiphilic block copolymers are known to prevent aggregation of unfolded proteins. To better understand the mechanism of this effect, the optical properties of heat-denatured and dithiothreitol (DTT) reduced lysozyme were evaluated with respect to controls using UV-Vis spectroscopy, transmi...

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Detalhes bibliográficos
Publicado no:Phys Biol
Main Authors: Chin, Jaemin, Mustafi, Devkumar, Poellmann, Michael J., Lee, Raphael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385145/
https://ncbi.nlm.nih.gov/pubmed/28061483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/aa5788
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