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A neuronal MCT2 knockdown in the rat somatosensory cortex reduces both the NMR lactate signal and the BOLD response during whisker stimulation

Although several in vitro and ex vivo evidence support the existence of lactate exchange between astrocytes and neurons, a direct demonstration in vivo is still lacking. In the present study, a lentiviral vector carrying a short hairpin RNA (shRNA) was used to downregulate the expression of the mono...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Mazuel, Leslie, Blanc, Jordy, Repond, Cendrine, Bouchaud, Véronique, Raffard, Gérard, Déglon, Nicole, Bonvento, Gilles, Pellerin, Luc, Bouzier-Sore, Anne-Karine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384673/
https://ncbi.nlm.nih.gov/pubmed/28388627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174990
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