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Development of Efficient AAV2/DJ-Based Viral Vectors to Selectively Downregulate the Expression of Neuronal or Astrocytic Target Proteins in the Rat Central Nervous System

Viral vectors have become very popular to overexpress or downregulate proteins of interest in different cell types. They conveniently allow the precise targeting of well-defined tissue areas, which is particularly useful in complex organs like the brain. In theory, each vector should have its own ce...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Jollé, Charlotte, Déglon, Nicole, Pythoud, Catherine, Bouzier-Sore, Anne-Karine, Pellerin, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710342/
https://ncbi.nlm.nih.gov/pubmed/31481874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00201
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