AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice

OBJECTIVE: Hepatic steatosis is the first step leading to non-alcoholic fatty liver disease, which represents a major complication of obesity. Here, we show that MCT1 haploinsufficient mice resist to hepatic steatosis development when fed a high fat diet. They exhibit a reduced hepatic capacity to m...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Metab
मुख्य लेखकों: Carneiro, Lionel, Asrih, Mohamed, Repond, Cendrine, Sempoux, Christine, Stehle, Jean-Christophe, Leloup, Corinne, Jornayvaz, François R., Pellerin, Luc
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2017
विषय:
Brief Communication
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699913/
https://ncbi.nlm.nih.gov/pubmed/29092796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.10.005
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन