BMP6 Regulates Proliferation and Apoptosis of Human Sertoli Cells Via Smad2/3 and Cyclin D1 Pathway and DACH1 and TFAP2A Activation

Sertoli cells are essential for regulating normal spermatogenesis. However, the mechanisms underlying human Sertoli cell development remain largely elusive. Here we examined the function and signaling pathways of BMP6 in regulating human Sertoli cells. RT-PCR, immunocytochemistry and Western blots r...

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Pubblicato in:Sci Rep
Autori principali: Wang, Hong, Yuan, Qingqing, Sun, Min, Niu, Minghui, Wen, Liping, Fu, Hongyong, Zhou, Fan, Chen, Zheng, Yao, Chencheng, Hou, Jingmei, Shen, Ruinan, Lin, Qisheng, Liu, Wenjie, Jia, Ruobing, Li, Zheng, He, Zuping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384448/
https://ncbi.nlm.nih.gov/pubmed/28387750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45298
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