Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation

BACKGROUND: Sertoli cells play key roles in regulating spermatogenesis and testis development by providing structural and nutritional supports. Recent studies demonstrate that Sertoli cells can be converted into functional neural stem cells. Adult Sertoli cells have previously been considered the te...

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Bibliographic Details
Published in:	Cell Commun Signal
Main Authors:	Guo, Ying, Hai, Yanan, Yao, Chencheng, Chen, Zheng, Hou, Jingmei, Li, Zheng, He, Zuping
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2015
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4380114/ https://ncbi.nlm.nih.gov/pubmed/25880873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0101-2
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Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation

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