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Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation

BACKGROUND: Sertoli cells play key roles in regulating spermatogenesis and testis development by providing structural and nutritional supports. Recent studies demonstrate that Sertoli cells can be converted into functional neural stem cells. Adult Sertoli cells have previously been considered the te...

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Dettagli Bibliografici
Pubblicato in:Cell Commun Signal
Autori principali: Guo, Ying, Hai, Yanan, Yao, Chencheng, Chen, Zheng, Hou, Jingmei, Li, Zheng, He, Zuping
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380114/
https://ncbi.nlm.nih.gov/pubmed/25880873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0101-2
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