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Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation

BACKGROUND: Sertoli cells play key roles in regulating spermatogenesis and testis development by providing structural and nutritional supports. Recent studies demonstrate that Sertoli cells can be converted into functional neural stem cells. Adult Sertoli cells have previously been considered the te...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Guo, Ying, Hai, Yanan, Yao, Chencheng, Chen, Zheng, Hou, Jingmei, Li, Zheng, He, Zuping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380114/
https://ncbi.nlm.nih.gov/pubmed/25880873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0101-2
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