BMP6 Regulates Proliferation and Apoptosis of Human Sertoli Cells Via Smad2/3 and Cyclin D1 Pathway and DACH1 and TFAP2A Activation

Sertoli cells are essential for regulating normal spermatogenesis. However, the mechanisms underlying human Sertoli cell development remain largely elusive. Here we examined the function and signaling pathways of BMP6 in regulating human Sertoli cells. RT-PCR, immunocytochemistry and Western blots r...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Wang, Hong, Yuan, Qingqing, Sun, Min, Niu, Minghui, Wen, Liping, Fu, Hongyong, Zhou, Fan, Chen, Zheng, Yao, Chencheng, Hou, Jingmei, Shen, Ruinan, Lin, Qisheng, Liu, Wenjie, Jia, Ruobing, Li, Zheng, He, Zuping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384448/
https://ncbi.nlm.nih.gov/pubmed/28387750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45298
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