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Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids

α-amino acids bearing aromatic side chains are important synthetic units in the synthesis of peptides and natural products. Although various β-C-H arylation methodologies for amino acid derivatives involving the assistance of directing groups have been extensively developed, syntheses that directly...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhu, Yan, Chen, Xiaolan, Yuan, Chunchen, Li, Guobao, Zhang, Jingyu, Zhao, Yingsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384235/
https://ncbi.nlm.nih.gov/pubmed/28383026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14904
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