Expression, Functional Characterization, and Solid-State NMR Investigation of the G Protein-Coupled GHS Receptor in Bilayer Membranes

The expression, functional reconstitution and first NMR characterization of the human growth hormone secretagogue (GHS) receptor reconstituted into either DMPC or POPC membranes is described. The receptor was expressed in E. coli. refolded, and reconstituted into bilayer membranes. The molecule was...

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Publicat a:Sci Rep
Autors principals: Schrottke, Stefanie, Kaiser, Anette, Vortmeier, Gerrit, Els-Heindl, Sylvia, Worm, Dennis, Bosse, Mathias, Schmidt, Peter, Scheidt, Holger A., Beck-Sickinger, Annette G., Huster, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384189/
https://ncbi.nlm.nih.gov/pubmed/28387359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46128
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