RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer

Breast cancer subtypes display distinct biological traits that influence their clinical behavior and response to therapy. Recent studies have highlighted the importance of chromatin structure regulators in tumorigenesis. The RNF20-RNF40 E3 ubiquitin ligase complex monoubiquitylates histone H2B to ge...

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Sparad:
Bibliografiska uppgifter
I publikationen:Cell Death Differ
Huvudupphovsmän: Tarcic, Ohad, Granit, Roy Z, Pateras, Ioannis S, Masury, Hadas, Maly, Bella, Zwang, Yaara, Yarden, Yosef, Gorgoulis, Vassilis G, Pikarsky, Eli, Ben-Porath, Ittai, Oren, Moshe
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384017/
https://ncbi.nlm.nih.gov/pubmed/28157208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.126
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