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p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy
The epidermal growth factor receptor (EGFR) frequently associates with cancer and already serves as a target for therapy. We report that inflammatory cytokines and ultraviolet (UV) irradiation respectively induce transient or sustained phosphorylation of EGFR. Subsequently, EGFR internalizes via a C...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1570432/ https://ncbi.nlm.nih.gov/pubmed/16932740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601297 |
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