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RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer
Breast cancer subtypes display distinct biological traits that influence their clinical behavior and response to therapy. Recent studies have highlighted the importance of chromatin structure regulators in tumorigenesis. The RNF20-RNF40 E3 ubiquitin ligase complex monoubiquitylates histone H2B to ge...
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| Veröffentlicht in: | Cell Death Differ |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5384017/ https://ncbi.nlm.nih.gov/pubmed/28157208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.126 |
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