RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer

Breast cancer subtypes display distinct biological traits that influence their clinical behavior and response to therapy. Recent studies have highlighted the importance of chromatin structure regulators in tumorigenesis. The RNF20-RNF40 E3 ubiquitin ligase complex monoubiquitylates histone H2B to ge...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Differ
Auteurs principaux: Tarcic, Ohad, Granit, Roy Z, Pateras, Ioannis S, Masury, Hadas, Maly, Bella, Zwang, Yaara, Yarden, Yosef, Gorgoulis, Vassilis G, Pikarsky, Eli, Ben-Porath, Ittai, Oren, Moshe
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384017/
https://ncbi.nlm.nih.gov/pubmed/28157208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.126
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