Comparing Oncology Clinical Programs by Use of Innovative Designs and Expected Net Present Value Optimization: Which Adaptive Approach Leads to the Best Result?

Designing an oncology clinical program is more challenging than designing a single study. The standard approaches have been proven to be not very successful during the last decade; the failure rate of Phase 2 and Phase 3 trials in oncology remains high. Improving a development strategy by applying i...

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Vydáno v:J Biopharm Stat
Hlavní autoři: Parke, Tom, Marchenko, Olga, Anisimov, Vladimir, Ivanova, Anastasia, Jennison, Christopher, Perevozskaya, Inna, Song, Guochen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383527/
https://ncbi.nlm.nih.gov/pubmed/28281911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2017.1289949
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