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KAT2-mediated PLK4 acetylation contributes to genomic stability by preserving centrosome number

We have recently identified the first human lysine (K) acetyltransferase 2A and 2B (called KAT2A/2B; known also as GCN5/PCAF, respectively)-dependent acetylome and revealed a mechanism by which KAT2A/2B-mediated acetylation of serine/threonine polo-like kinase 4 (PLK4) maintains correct centrosome n...

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Veröffentlicht in:Mol Cell Oncol
Hauptverfasser: Fournier, Marjorie, Tora, László
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383365/
https://ncbi.nlm.nih.gov/pubmed/28401181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1270391
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