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KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification

Lysine acetylation is a widespread post-translational modification regulating various biological processes. To characterize cellular functions of the human lysine acetyltransferases KAT2A (GCN5) and KAT2B (PCAF), we determined their acetylome by shotgun proteomics. One of the newly identified KAT2A/...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fournier, Marjorie, Orpinell, Meritxell, Grauffel, Cédric, Scheer, Elisabeth, Garnier, Jean-Marie, Ye, Tao, Chavant, Virginie, Joint, Mathilde, Esashi, Fumiko, Dejaegere, Annick, Gönczy, Pierre, Tora, László
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095585/
https://ncbi.nlm.nih.gov/pubmed/27796307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13227
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