Inhibition of EZH2 degradation as a novel approach to overcome drug resistance in acute myeloid leukemia

The polycomb protein enhancer of zeste homolog 2 (EZH2) may have a dual role in cancer pathogenesis acting as an oncogene or as a tumor suppressor depending on the cancer type. We recently demonstrated that proteasomal degradation of EZH2 resulting from cyclin-dependent kinase 1 (CDK1)-induced phosp...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Göllner, Stefanie, Müller-Tidow, Carsten
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Author's View
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383362/
https://ncbi.nlm.nih.gov/pubmed/28401191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1291396
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker