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Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA
The innate-immune restriction factor MxA inhibits influenza replication by targeting the viral nucleoprotein (NP). Human influenza virus is more resistant than avian influenza virus to inhibition by human MxA, and prior work has compared human and avian viral strains to identify amino-acid differenc...
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| Yayımlandı: | PLoS Pathog |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5383324/ https://ncbi.nlm.nih.gov/pubmed/28346537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006288 |
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