The Viral Nucleoprotein Determines Mx Sensitivity of Influenza A Viruses

Host restriction factors play a crucial role in preventing trans-species transmission of viral pathogens. In mammals, the interferon-induced Mx GTPases are powerful antiviral proteins restricting orthomyxoviruses. Hence, the human MxA GTPase may function as an efficient barrier against zoonotic intr...

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Main Authors: Zimmermann, Petra, Mänz, Benjamin, Haller, Otto, Schwemmle, Martin, Kochs, Georg
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Cellular Response to Infection
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147989/
https://ncbi.nlm.nih.gov/pubmed/21680506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00712-11
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