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Tick-transmitted thogotovirus gains high virulence by a single MxA escape mutation in the viral nucleoprotein

Infections with emerging and re-emerging arboviruses are of increasing concern for global health. Tick-transmitted RNA viruses of the genus Thogotovirus in the Orthomyxoviridae family have considerable zoonotic potential, as indicated by the recent emergence of Bourbon virus in the USA. To successfu...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Fuchs, Jonas, Oschwald, Alexander, Graf, Laura, Kochs, Georg
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704052/
https://ncbi.nlm.nih.gov/pubmed/33196685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009038
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