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Accurate predictions of population-level changes in sequence and structural properties of HIV-1 Env using a volatility-controlled diffusion model

The envelope glycoproteins (Envs) of HIV-1 continuously evolve in the host by random mutations and recombination events. The resulting diversity of Env variants circulating in the population and their continuing diversification process limit the efficacy of AIDS vaccines. We examined the historic ch...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS Biol
Κύριοι συγγραφείς: DeLeon, Orlando, Hodis, Hagit, O’Malley, Yunxia, Johnson, Jacklyn, Salimi, Hamid, Zhai, Yinjie, Winter, Elizabeth, Remec, Claire, Eichelberger, Noah, Van Cleave, Brandon, Puliadi, Ramya, Harrington, Robert D., Stapleton, Jack T., Haim, Hillel
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383018/
https://ncbi.nlm.nih.gov/pubmed/28384158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001549
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