Key Positions of HIV-1 Env and Signatures of Vaccine Efficacy Show Gradual Reduction of Population Founder Effects at the Clade and Regional Levels

HIV-1 group M was transmitted to humans nearly one century ago. The virus has since evolved to form distinct clades, which spread to different regions of the world. The envelope glycoproteins (Envs) of HIV-1 have rapidly diversified in all infected populations. We examined whether key antigenic site...

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Опубликовано в: :mBio
Главные авторы: Han, Changze, Johnson, Jacklyn, Dong, Rentian, Kandula, Raghavendranath, Kort, Alexa, Wong, Maria, Yang, Tianbao, Breheny, Patrick J., Brown, Grant D., Haim, Hillel
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373194/
https://ncbi.nlm.nih.gov/pubmed/32518179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00126-20
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