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Modeling Virus- and Antibody-Specific Factors to Predict Human Immunodeficiency Virus (HIV-1) Neutralization Efficiency

Efforts to prevent human immunodeficiency virus (HIV-1) infection would benefit from understanding the factors that govern virus neutralization by antibodies. We present a mechanistic model for HIV-1 neutralization that includes both virus and antibody parameters. Variations in epitope integrity on...

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書誌詳細
主要な著者: Haim, Hillel, Salas, Ignacio, McGee, Kathleen, Eichelberger, Noah, Winter, Elizabeth, Pacheco, Beatriz, Sodroski, Joseph
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875163/
https://ncbi.nlm.nih.gov/pubmed/24237700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.10.006
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