Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a progressive upper and lower motor neuron degeneration. One of the peculiar clinical characteristics of ALS is the wide distribution in age of onset, which is probably caused by different combinations of intri...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Filareti, Melania, Luotti, Silvia, Pasetto, Laura, Pignataro, Mauro, Paolella, Katia, Messina, Paolo, Pupillo, Elisabetta, Filosto, Massimiliano, Lunetta, Christian, Mandrioli, Jessica, Fuda, Giuseppe, Calvo, Andrea, Chiò, Adriano, Corbo, Massimo, Bendotti, Caterina, Beghi, Ettore, Bonetto, Valentina
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382314/
https://ncbi.nlm.nih.gov/pubmed/28428745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00099
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