Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a progressive upper and lower motor neuron degeneration. One of the peculiar clinical characteristics of ALS is the wide distribution in age of onset, which is probably caused by different combinations of intri...

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Pubblicato in:Front Mol Neurosci
Autori principali: Filareti, Melania, Luotti, Silvia, Pasetto, Laura, Pignataro, Mauro, Paolella, Katia, Messina, Paolo, Pupillo, Elisabetta, Filosto, Massimiliano, Lunetta, Christian, Mandrioli, Jessica, Fuda, Giuseppe, Calvo, Andrea, Chiò, Adriano, Corbo, Massimo, Bendotti, Caterina, Beghi, Ettore, Bonetto, Valentina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382314/
https://ncbi.nlm.nih.gov/pubmed/28428745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00099
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